An enzyme with self-control
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چکیده
منابع مشابه
An enzyme with self-control
U nlike enzymes that depend on other proteins to rein in their activity, polo-like kinase 4 (Plk4) does the job itself. Holland et al. reveal that Plk4, which helps regulate centro-some duplication, reduces its activity by initiating its own destruction (1). By sacrifi cing itself, the protein prevents cells from building too many centrosomes. Cells prepare to divide by duplicating the centroso...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2010
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1882if